Objectives: Review of preoperative evaluation, surgical management, an
d outcome of patients operated on for nasopharyngeal angiofibroma usin
g lateral infratemporal fossa approaches. Study Design: Retrospective
review of 20 patients with either extensive (Fisch class IIa to IVb, n
= 17) or less massive (Fisch class II, n = 3) nasopharyngeal angiofib
romas. Analysis of preoperative radiologic classification and angiogra
phy and description of indications and surgical techniques of the infr
atemporal fossa approaches types C and D. Evaluation of the surgical m
orbidity and radicality of tumor removal. Methods: Clinical data were
obtained from medical records from 1987 to 1994. Tumor classification,
preoperative symptoms type of surgery, and neuroradiologic and surgic
al complications were evaluated. The completeness of tumor removal was
assessed using postoperative magnetic resonance imaging. Results: Tem
porary visual disturbance or headache, or both, was seen in two of 20
patients after superselective tumor embolization and further visual di
minution was observed in one of six patients after balloon occlusion o
f the internal carotoid artery. Radical resection was obtained in 80%
of the cases. The infratemporal fossa type C approach was used in 16 o
f the cases, with type D approaches used in the other four. There were
no deaths. The major morbidity was the conductive hearing loss associ
ated with the C approach. Conclusions: Preoperative embolization (and
balloon occlusion in selected cases) remains an important adjunct with
minimal morbidity. The lateral infratemporal fossa approaches yield a
high rate of radical tumor removal (80%) and a low rate of recurrence
(6%). If applicable, the type D approach avoids the conductive hearin
g loss but allows direct tumor access into the infratemporal and ptery
gopalatine fossae.