RISK-FACTORS FOR PROSTHETIC JOINT INFECTION - CASE-CONTROL STUDY

We conducted a matched case-control study tea determine risk factors f or the development of prosthetic joint infection. Cases were patients with prosthetic hip or knee joint infection. Controls were patients wh o underwent total hip or knee arthroplasty and did not develop prosthe tic joint infection. A multiple logistic regression model indicated th at risk factors for prosthetic joint infection were the development of a surgical site infection not involving the prosthesis (odds ratio [O R], 35.9; 95% confidence interval [CI], 8.3-154.6), a National Nosocom ial Infections Surveillance (NNIS) System surgical patient risk index score of 1 (OR, 1.7; 95% CI, 1.2-2.3) or 2 (OR, 3.9; 95% CI, 2.0-7.5), the presence of a malignancy (OR, 3.1; 95% CI, 1.3-7.2)., and a histo ry of joint arthroplasty (OR, 2.0; 95% CI, 1.4-3.0). Our findings sugg est that a surgical site infection not involving the joint prosthesis, an NNIS System surgical patient risk index score of 1 or 2, the prese nce of a malignancy, and a history of a joint arthroplasty are associa ted with an increased risk of prosthetic joint infection.