Caries have three main interrelated etiological factors: 1) a bacterio
logical factor represented by cariogen oral bacteria, mainly Streptoco
ccus mutans, which adhere to the dental surface and initiate the decal
cification of the enamel by producing an acid environment through carb
ohydrate degradation; 2) the quality of the oral biofilm which is colo
nized more or less rapidly by bacteria after brushing, leading to an a
dhesive and aggressive dental plaque; 3) the quality of enamel which i
s reinforced by fluor ion, and of saliva. The early superficial phase
of carie constitution is reversible through remineralisation from calc
ium, phosphate and fluor ions present in the oral cavity. In the absen
ce of remineralisation the destructive and infectious process extends
to the inner part of the tooth leading, to ifs progressive destruction
. Prevention is based upon the following pathophysiological data, main
ly: 1) family education on oral hygiene by regular brushing, and avoid
ance of foods or fluids containing sugars between meals; 2) fluoride i
ntake starting at birth and being adapted to age, the prescription of
fluoride supplementation, taking into account possible other sources o
f fluor (salt, water). (C) 1998 Elsevier, Paris.