We study the loop expansion for the low energy effective action for ma
trix string theory. For long string configurations we find the result
depends on the ordering of limits. Taking g(s) --> 0 before N --> infi
nity we find free strings. Reversing the order of limits however we fi
nd anomalous contributions coming from the large N limit that invalida
te the loop expansion. We then embed the classical instanton solution
corresponding to a high energy string interaction into a long string c
onfiguration. We find the instanton has a loop expansion weighted by f
ractional positive powers of N. Finally we identify the scaling regime
for which interacting long string configurations have a loop expansio
n with a well defined large N limit. The limit corresponds to large ''
classical'' strings and can be identified with the ''dual'' of the 't
Hooft limit, g(SYM)(2) similar to N. (C) 1998 Elsevier Science B.V. Al
l rights reserved.