E. Nakamura et al., PAPILLARY SQUAMOUS-CELL CARCINOMA OF THE UTERINE CERVIX - DIAGNOSTIC PITFALLS, APMIS. Acta pathologica, microbiologica et immunologica Scandinavica, 106(10), 1998, pp. 975-978
A case of papillary squamous cell carcinoma (PSCC) of the uterine cerv
ix is reported. The patient was a 73-year-old Japanese woman with acut
e renal failure and bilateral hydronephrosis. A cauliflower-like mass
was found in the uterine cervix. A uterine cervical biopsy specimen re
vealed PSCC in situ, while clinically it was an invasive carcinoma. Ut
erine cervical biopsy was performed a second time to confirm its strom
al invasion. However, only small fragments were obtained because of he
avy bleeding from the tumor and they showed PSCC in situ again. Follow
ing this, computed tomography of the pelvis revealed a 5 cm mass in th
e uterine cervix, invading the vagina and urinary bladder. Though deep
-wedge biopsy, loop electrosurgical excision, or cone biopsy is recomm
ended to evaluate PSCC, it may be impossible to perform any of these p
rocedures because of bleeding such as that seen in our case. In these
circumstances, good communication between pathologists and clinicians
is important since lack of communication may cause PSCC to be microsco
pically misinterpreted as in situ carcinoma rather than invasive carci
noma.