POLY(ADP-RIBOSE)POLYMERASE, A POTENTIAL TARGET FOR DRUGS - PART II - REGULATION OF DIFFERENTIATION BY THE POLY-ADP-RIBOSE SYSTEM

Authors
KUN E
Citation
E. Kun, POLY(ADP-RIBOSE)POLYMERASE, A POTENTIAL TARGET FOR DRUGS - PART II - REGULATION OF DIFFERENTIATION BY THE POLY-ADP-RIBOSE SYSTEM, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2(5), 1998, pp. 591-592
Citations number
6
Categorie Soggetti
Medicine, Research & Experimental
Journal title
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE → ACNP
ISSN journal
11073756
Volume
2
Issue
5
Year of publication
1998
Pages
591 - 592
Database
ISI
SICI code
1107-3756(1998)2:5<591:PAPTFD>2.0.ZU;2-Y
Abstract
It is shown that eukaryotic differentiation is specifically sensitive to pADPRT regulation in Trypanosoma, Leishmania and Mytilus models. Th ere is powerful inhibition of early differentiation without cell toxic ity by pADPRT ligands.