ANGIOTENSIN-II RECEPTORS ON COLORECTAL-CARCINOMA CELLS

Citation
D. Kucerova et al., ANGIOTENSIN-II RECEPTORS ON COLORECTAL-CARCINOMA CELLS, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2(5), 1998, pp. 593-595
Citations number
24
Categorie Soggetti
Medicine, Research & Experimental
ISSN journal
11073756
Volume
2
Issue
5
Year of publication
1998
Pages
593 - 595
Database
ISI
SICI code
1107-3756(1998)2:5<593:AROCC>2.0.ZU;2-1
Abstract
The presence of angiotensin II receptors was found on cells of three c olorectal carcinoma cell lines. The binding assays with I-125-labelled angiotensin II and ligands specific for angiotensin AT(1) or AT(2) re ceptors showed that angiotensin receptors on colorectal cancer cells a re mostly of the AT(2) type. The binding capacity of tumor cells was n ot significantly changed by butyrate-induced differentiation.