I. Mouyna et al., A 1,3-BETA-GLUCANOSYLTRANSFERASE ISOLATED FROM THE CELL-WALL OF ASPERGILLUS-FUMIGATUS IS A HOMOLOG OF THE YEAST BGL2P, Microbiology, 144, 1998, pp. 3171-3180
A 1,3-beta-gtucanosyltransferase which introduces intrachain 1,6-beta
linkages into 1,3-beta-glucan was isolated from the cell wall of Asper
gillus fumigatus. The biochemical and molecular characterization of th
e A. fumigatus transferase showed it was homologous to the Saccharomyc
es cerevisiae and Candida albicans transferase Bg12p. A null mutant co
nstructed in A. fumigatus by gene replacement did not show a distinct
phenotype from the parental strain. The putative function of this majo
r cell-wail-associated protein is discussed.