D. Riesenbeck et al., PHOTOGRAPHIC DOCUMENTATION OF ACUTE RADIATION-INDUCED SIDE-EFFECTS OFTHE ORAL-MUCOSA, Strahlentherapie und Onkologie, 174, 1998, pp. 40-43
Citations number
12
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Background: Radiotherapy in cancer of the head and neck induces cutane
ous and mucosal reactions. These must be carefully assessed and docume
ntated to control the accuracy of individual treatment, the overall to
xicity of particular treatment schedules, the efficacy of prophylaxis
and treatment and to determine the adequate therapy of treatment seque
lae depending on the severity of the reactions. The accurate classific
ation of lesions according to internationally accepted schedules (WHO/
RTOG/CTC) is indispensable for the comparison of radiotherapy treatmen
t results and efficacy of supportive care. Methods: While the treatmen
t of cancer depends on tumor stage and medical circumstances of the pa
tient and is more or less standardized, prophylaxis and treatment of s
ide-effects is highly variable. Discussing an optimized prophylaxis an
d therapy of oral mucositis, the problem of accurate classification an
d documentation emerged. The verbal description of mucosal lesions is
open to many subjective interpretations. Photographic documentation se
ems a suitable method to optimize the grading of toxicity. Results: A
photographic survey of typical lesions for each grade of toxicity is a
tool to reach several aims in one step. Toxicity of an individual pat
ient may be compared with representative photographic examples in dail
y routine to decide quickly on the grade of toxicity. Subjective diffe
rences due to intra- and interpersonal variability of the evaluating r
a diooncologist will be reduced. The efficacy of treatment can be prov
en by accurate documentation. Randomized clinical studies concerning p
rophylaxis and treatment of oral mucositis will provide more reliable
results if evaluation of toxicity grading is standardized by photograp
hs. Conclusions: Photographic documentation of lesions of the oral muc
osa might be the best means to reduce interindividual subjectivity in
grading. It is a valuable appendix to standard classification systems
and only concerns the visible signs of mucosal lesions. However, the e
xact grading of mucositis is only possible with additional clinical in
formation about pain and nutritional situation.