Parametric regression on cumulative incidence function

Citation
Jeong, Jong-hyeon et P. Fine, Jason, Parametric regression on cumulative incidence function, Biostatistics (Oxford. Print) , 8(2), 2007, pp. 184-196
ISSN journal
14654644
Volume
8
Issue
2
Year of publication
2007
Pages
184 - 196
Database
ACNP
SICI code
Abstract
We propose parametric regression analysis of cumulative incidence function with competing risks data.A simple form of Gompertz distribution is used for the improper baseline subdistribution of the event of interest.Maximum likelihood inferences on regression parameters and associated cumulative incidence function are developed for parametric models, including a flexible generalized odds rate model.Estimation of the long-term proportion of patients with cause-specific events is straightforward in the parametric setting.Simple goodness-of-fit tests are discussed for evaluating a fixed odds rate assumption.The parametric regression methods are compared with an existing semiparametric regression analysis on a breast cancer data set where the cumulative incidence of recurrence is of interest.The results demonstrate that the likelihood-based parametric analyses for the cumulative incidence function are a practically useful alternative to the semiparametric analyses.