M. Okeefe et al., LONGER TERM VISUAL OUTCOME OF EYES WITH RETINOPATHY OF PREMATURITY TREATED WITH CRYOTHERAPY OR DIODE-LASER, British journal of ophthalmology, 82(11), 1998, pp. 1246-1248
Aims-Visual outcome of 66 eyes in 37 patients who had undergone treatm
ent with either cryotherapy or diode laser for threshold retinopathy o
f prematurity was assessed. Methods-17 patients, representing 30 eyes
treated with cryotherapy, were examined at between 56 and 98 months co
rrected age (median 68 months). 20 patients representing 36 eyes treat
ed with diode laser, were examined at between 30 and 66 months correct
ed age (median 51 months). Structural outcome was categorised as: opti
mal-flat posterior pole; suboptimal-macular ectopia, optic nerve hypop
lasia, retinal fold involving the macula, and retinal detachment invol
ving the macula. Results-Optimal structural outcome was, in the absenc
e of amblyopia, associated with optimal visual acuity (of 6/12 or bett
er) in all cases, with most eyes achieving a visual acuity of 6/9 or 6
/6. Suboptimal structural outcome was invariably associated with subop
timal visual acuity. Amblyopia was present in eight out of 20 cryother
apy treated eyes and in five out of 26 laser treated eyes with an opti
mal structural outcome. Refractive errors were significantly less in l
aser treated eyes as was the incidence of anisometropic amblyopia. Con
clusion-Eyes treated with either cryotherapy or diode laser for thresh
old retinopathy of prematurity with optimal structural outcome are ass
ociated with development of optimal visual acuity-that is, 6/12 or bet
ter. Treatment with either cryotherapy or laser does not in itself red
uce the visual potential of these eyes.