Background: Maternal smoking negatively affects bir th weight, breast
milk volume and growth at one month of age. Aim: To study the effect o
f maternal smoking on the growth of three month old infants. Subjects
and methods: Ten smoking and 10 non smoking mothers with one month old
children, under exclusive breast feeding, were selected for the study
. Urinary cotinine levels in the mothers and children were measured to
assess smoking. Two months later; children were reassessed. Results:
Smoking mothers consumed a mean of 6.5 cigarettes/day. Compared to non
smokers, urinary continine levels were higher in these mothers (60 +/
- 22 and 1428 +/- 716 ng/ml respectively, P < 0.002) and their offspri
ng (21 +/- 20 and 156 +/- 101 ng/ml respectively p < 0.001). Compared
with smokers, at three months of age, children of non smoking mothers
had a higher average weight (5829 +/- 498 and 6325 +/- 427 g, P < 0.02
). Conclusions: Measurement of urinary continue levels is a reliable a
nd objective measure of maternal smoking and nicotine transfer to the
offspring. It also allows the assessment of passive smoking. Maternal
smoking adversely affects child growth at three months of age.