THE STRUCTURE OF A,4,5,9B-TETRAHYDROISOQUINOLINO-[1,2B]THIAZOLIDINE

The crystal structure of 7,8 hoxy-3-oxo-3a,4,5,9b-tetrahydroisoquinoli no-[1,2b] thiazolidine has been investigated by X-ray diffraction meth ods. Crystals are monoclinic, space group P2(1)/c, a = 19.789(2), b = 7.454(1), c = 8.917 Angstrom, beta = 100.43(1)degrees, Z = 4. The stru cture was solved by direct methods and refined to R = 0.0329 for 2110 observed reflections. The slim of three bond angles around N atom is 3 59.3(3)degrees, showing its near planar surrounding. The tetrahydroiso quinoline moiety is composed of the planar aromatic ring and hydrogena ted heterocyclic ring having the conformation of non-ideal sofa. The n ext condensed heterocyclic five-membered ring accepts the form of enve lope. This is the first published crystal structure of tetrahydroisoqu inoline moiety fused with sulfur containing five-membered ring.