We report the first case of synchronous Paget's disease of the vulva a
nd breast diagnosed within a period of 7 months. This is the fourth ca
se of mammary Paget's disease associated with either preceding or foll
owing vulvar Paget's disease documented in the literature. With consid
eration of increasing age of the population, and the fact that vulvar
Paget's disease affects elderly women and that breast cancer is the mo
st common malignancy of women in the United States, one can anticipate
the occurrence of these two conditions to be more prevalent in the fu
ture. (C) 1998 Academic Press.