T. Sugiyama et al., 2 CASES OF ENDOMETRIAL ADENOCARCINOMA ARISING FROM ATYPICAL POLYPOID ADENOMYOMA, Gynecologic oncology (Print), 71(1), 1998, pp. 141-144
Atypical polypoid adenomyoma (APA) most frequently presents as an endo
metrial polyp in premenopausal women and is believed to follow a benig
n course. In hysterectomy specimens from postmenopausal Japanease wome
n, the endometrium contained an APA with an area of endometrial adenoc
arcinoma. A convincing transition zone between the APA and the adenoca
rcinoma was seen in our cases, suggesting that APA may develop into en
dometrial adenocarcinoma in postmenopausal women. (C) 1998 Academic Pr
ess.