LITHIUM PERCHLORATE MEDIATED ALLYLIC SUBSTITUTION-REACTION USING A CYCLOHEXENYL BASED MODEL SYSTEM

Authors
SMITH CC ROTHHAAR RR THOBE KJ CRAGO CM PEKELNICKY P
Citation
Cc. Smith et al., LITHIUM PERCHLORATE MEDIATED ALLYLIC SUBSTITUTION-REACTION USING A CYCLOHEXENYL BASED MODEL SYSTEM, Microchemical journal, 56(1), 1997, pp. 65-78
Citations number
25
Categorie Soggetti
Chemistry Analytical
Journal title
Microchemical journal → ACNP
ISSN journal
0026265X
Volume
56
Issue
1
Year of publication
1997
Pages
65 - 78
Database
ISI
SICI code
0026-265X(1997)56:1<65:LPMASU>2.0.ZU;2-A
Abstract
A methodology was developed for the direct substitution of allylic alc ohols and acetates by alcohol nucleophiles in order to synthesize ally lic ethers. The reaction was mediated by highly concentrated ethereal solutions of lithium perchlorate and proceeded with high regiospecific ity. Additionally, the methodology was extended to enable allyl ether exchanges to occur. (C) 1997 Academic Press.