SYNTHESIS OF NOVEL C7-ARYL SUBSTITUTED PYRROLO[2,1-C][1,4]BENZODIAZEPINES (PBDS) VIA PRO-N-10-TROC PROTECTION AND SUZUKI COUPLING

Authors
GUIOTTO A HOWARD PW BARALDI PG THURSTON DE
Citation
A. Guiotto et al., SYNTHESIS OF NOVEL C7-ARYL SUBSTITUTED PYRROLO[2,1-C][1,4]BENZODIAZEPINES (PBDS) VIA PRO-N-10-TROC PROTECTION AND SUZUKI COUPLING, Bioorganic & medicinal chemistry letters, 8(21), 1998, pp. 3017-3018
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
21
Year of publication
1998
Pages
3017 - 3018
Database
ISI
SICI code
0960-894X(1998)8:21<3017:SONCSP>2.0.ZU;2-3
Abstract
Novel C7-aryl pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) have been synt hesized via Suzuki coupling between a 7-Iodo N10-Troc-protected PBD ca rbinolamine and commercially available boronic acids, (C) 1998 Elsevie r Science Ltd. All rights reserved.