SYNTHESIS OF A SERIES OF SULFINIC ACID ANALOGS OF GABA AND EVALUATIONOF THEIR GABA(A) RECEPTOR AFFINITIES

Authors
CARRUTHERS NI SPITLER JM WONG SC BLYTHIN DJ CHEN X SHUE HJ SHE HS LEE JF RIZZO C TING PC WEST RE
Citation
Ni. Carruthers et al., SYNTHESIS OF A SERIES OF SULFINIC ACID ANALOGS OF GABA AND EVALUATIONOF THEIR GABA(A) RECEPTOR AFFINITIES, Bioorganic & medicinal chemistry letters, 8(21), 1998, pp. 3059-3064
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
21
Year of publication
1998
Pages
3059 - 3064
Database
ISI
SICI code
0960-894X(1998)8:21<3059:SOASOS>2.0.ZU;2-N
Abstract
A series of gamma-aminobutyric acid (GABA) I analogs was prepared in w hich the carboxylic acid group of GABA was replaced with a sulfinic ac id group and their affinity for the GABAB receptor investigated. (C) 1 998 Elsevier Science Ltd. All rights reserved.