ELECTROCHEMICAL STUDIES OF S-NITROSOTHIOLS

Authors
HOU YC WANG JQ ARIAS F ECHEGOYEN L WANG PG
Citation
Yc. Hou et al., ELECTROCHEMICAL STUDIES OF S-NITROSOTHIOLS, Bioorganic & medicinal chemistry letters, 8(21), 1998, pp. 3065-3070
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
21
Year of publication
1998
Pages
3065 - 3070
Database
ISI
SICI code
0960-894X(1998)8:21<3065:ESOS>2.0.ZU;2-9
Abstract
S-nitrosothiols (RSNO), such as SNAP, GSNO, and Glc-SNAP-1 exhibited a single, totally irreversible, diffusion controlled reduction peak at potentials of -0.97 V, -0.98 V and -0.91 V, respectively, vs. Ag/AgCl (3 M NaCl) reference electrode. This corresponded to the nitric oxide (NO) release from the S-nitrosothiols. A possible mechanism is propose d for the reduction process. (C) 1998 Elsevier Science Ltd. All rights reserved.