SYNTHESIS OF NOVEL CHIRAL QUATERNARY PHOSPHONIUM SALTS WITH A MULTIPLE HYDROGEN-BONDING SITE, AND THEIR APPLICATION TO ASYMMETRIC PHASE-TRANSFER ALKYLATION

Authors
MANABE K
Citation
K. Manabe, SYNTHESIS OF NOVEL CHIRAL QUATERNARY PHOSPHONIUM SALTS WITH A MULTIPLE HYDROGEN-BONDING SITE, AND THEIR APPLICATION TO ASYMMETRIC PHASE-TRANSFER ALKYLATION, Tetrahedron, 54(48), 1998, pp. 14465-14476
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
48
Year of publication
1998
Pages
14465 - 14476
Database
ISI
SICI code
0040-4020(1998)54:48<14465:SONCQP>2.0.ZU;2-X
Abstract
Chiral phosphonium salts having two NH and two OH groups as hydrogen-b ond donors have been synthesized as novel phase-transfer catalysts, an d used for asymmetric alkylation of beta-keto esters to give the corre sponding products with up to 50% ee. (C) 1998 Elsevier Science Ltd. Al l rights reserved.