THE INHIBITION OF BRAIN ACETYLCHOLINESTERASE ACTIVITY OF JUVENILE LARGEMOUTH BASS MICROPTERUS-SALMOIDES BY SUBLETHAL CONCENTRATIONS OF DIAZINON

Authors
PAN GZ DUTTA HM
Citation
Gz. Pan et Hm. Dutta, THE INHIBITION OF BRAIN ACETYLCHOLINESTERASE ACTIVITY OF JUVENILE LARGEMOUTH BASS MICROPTERUS-SALMOIDES BY SUBLETHAL CONCENTRATIONS OF DIAZINON, Environmental research (New York, N.Y. : Print), 79(2), 1998, pp. 133-137
Citations number
28
Categorie Soggetti
Public, Environmental & Occupation Heath","Environmental Sciences
Journal title
Environmental research (New York, N.Y. : Print) → ACNP
ISSN journal
00139351
Volume
79
Issue
2
Year of publication
1998
Pages
133 - 137
Database
ISI
SICI code
0013-9351(1998)79:2<133:TIOBAA>2.0.ZU;2-J
Abstract
An effect of diazinon on brain acetylcholinesterase (AChE) activity of juvenile largemouth bass Micropterus salmoides was observed. The expo sure concentration started from 1/10 of the 24-h LC50 value, 90 mu g/l iter. The exposure duration was 24 h. Statistically significant and do se-dependent reductions in the mean AChE activities we seen at 90, 180 , 270, 360, and 450 mu g/liter. The results show that juvenile brain a cetylcholinesterase activities were significantly inhibited by subleth al doses of diazinon. Inhibition of brain AChE will definitely cause p hysiological and behavioral modifications that reduce survival ability of the animals at an early stage Of growth. (C) 1998 Academic Press.