REAL-TIME IMAGING OF GENE-EXPRESSION IN SINGLE LIVING CELLS

Authors
RUTTER GA KENNEDY HJ WOOD CD WHITE MRH TAVARE JM
Citation
Ga. Rutter et al., REAL-TIME IMAGING OF GENE-EXPRESSION IN SINGLE LIVING CELLS, Chemistry & biology, 5(11), 1998, pp. 285-290
Citations number
27
Categorie Soggetti
Biology
Journal title
Chemistry & biology → ACNP
ISSN journal
10745521
Volume
5
Issue
11
Year of publication
1998
Pages
285 - 290
Database
ISI
SICI code
1074-5521(1998)5:11<285:RIOGIS>2.0.ZU;2-K
Abstract
Recent advances in reporter gene technologies are now allowing us to i mage gene transcription at the single cell level, using either fluores cence or luminescence microscopy. Here, the basis of these techniques is outlined and their advantages and disadvantages in various biologic al systems are discussed.