PHARMACOLOGICAL CHARACTERIZATION OF SYNAPTIC TRANSMISSION THROUGH MGLURS IN RAT CEREBELLAR SLICES

Authors
BATCHELOR AM KNOPFEL T GASPARINI F GARTHWAITE J
Citation
Am. Batchelor et al., PHARMACOLOGICAL CHARACTERIZATION OF SYNAPTIC TRANSMISSION THROUGH MGLURS IN RAT CEREBELLAR SLICES, Neuropharmacology, 36(3), 1997, pp. 401-403
Citations number
13
Categorie Soggetti
Pharmacology & Pharmacy",Neurosciences
Journal title
Neuropharmacology → ACNP
ISSN journal
00283908
Volume
36
Issue
3
Year of publication
1997
Pages
401 - 403
Database
ISI
SICI code
0028-3908(1997)36:3<401:PCOSTT>2.0.ZU;2-H
Abstract
The mGluR-mediated EPSP at parallel fibre-Purkinje cell synapses in th e cerebellum was blacked concentration-dependently and reversibly by a ntagonists acting selectively on group-I mGluRs but not by an inhibito r of group-III receptors. The results provide pharmacological evidence that the receptor type responsible for the mGluR-EPSP is mGluR1. (C) 1997 Elsevier Science Ltd.