On a generalized false discovery rate

Citation
K. Sarkar, Sanat et Guo, Wenge, On a generalized false discovery rate, Annals of statistics , 37(3), 2009, pp. 1545-1565
Journal title
ISSN journal
00905364
Volume
37
Issue
3
Year of publication
2009
Pages
1545 - 1565
Database
ACNP
SICI code
Abstract
The concept of k-FWER has received much attention lately as an appropriate error rate for multiple testing when one seeks to control at least k false rejections, for some fixed k.1. A less conservative notion, the k-FDR, has been introduced very recently by Sarkar [Ann. Statist. 34 (2006) 394.415], generalizing the false discovery rate of Benjamini and Hochberg [J. Roy. Statist. Soc. Ser. B 57 (1995) 289.300]. In this article, we bring newer insight to the k-FDR considering a mixture model involving independent p-values before motivating the developments of some new procedures that control it. We prove the k-FDR control of the proposed methods under a slightly weaker condition than in the mixture model. We provide numerical evidence of the proposed methods. superior power performance over some k-FWER and k-FDR methods. Finally, we apply our methods to a real data set.