HEPATOBILIARY CYSTADENOMA CAN PROTRUDE AND GROW INTO THE BILE-DUCTS

BACKGROUND/AIMS: To evaluate the phenomenon and the potential reasons for protrusion and growth Of hepatobiliary cystadenoma into the extrah epatic bile ducts in our patients, accomplished by a review of the dat a regarding hepatobiliary cystadenomas published elsewhere. METHODOLOG Y: In a retrospective open study conducted over the last eight years, five patients with hepatobiliary cystadenoma and one patient with hepa tobiliary cystadenocarcinoma were operated on. All the patients were f emales aged between 25 to 61 years. Diagnostic procedures, laboratory, operative and histopathological findings and treatment were evaluated . RESULTS: Most of our patients were found to have hepatobiliary cysta denoma located in the left surgical liver. In three out of five patien ts with HBC mesenchymal stroma was histologically detected. In two of the three, protrusion and growth into the extrahepatic bile ducts was found. CONCLUSION: Considering the pathogenesis, location and the morp hology of HBC, the mesenchymal stroma may present the competent potent ial for intraductal progression of the tumor. Radical excision should be performed for successful treatment of hepatobiliary cystadenomas, b ecause of the potential for reoccurrence.