K. Murata et al., LONG-TERM EFFECT OF PROPHYLACTIC ENDOSCOPIC INJECTION SCLEROTHERAPY ON LIVER-FUNCTION, Hepato-gastroenterology, 45(23), 1998, pp. 1726-1730
BACKGROUND/AIMS: The aim of this study was to investigate the long ter
m effect of prophylactic endoscopic injection sclerotherapy (EIS) on l
iver function. METHODOLOGY: This study was a retrospective investigati
on of seventy-eight patients with liver cirrhosis, whose liver functio
n was classified as Child's A before follow-up. Laboratory data were r
etrospectively examined before and after follow-up, and a comparison w
as made between the EIS group (n=21) and the non-treated group (n=57).
RESULTS: In the 3 or more years of follow-up, cholinesterase and tota
l cholesterol levels deteriorated in several severe-variceal cases. Ho
wever, these levels did not deteriorate over the 3 or more years of fo
llow-up in the EIS group.CONCLUSION: Prophylactic endoscopic injection
sclerotherapy among patients with early stage LC may prevent the dete
rioration of liver function.