P. Flemming et al., BENIGN SCHWANNOMA OF THE LIVER WITH CYSTIC CHANGES MISINTERPRETED AS HYDATID-DISEASE, Hepato-gastroenterology, 45(23), 1998, pp. 1764-1766
The rare event of a benign mesenchymal tumor of the liver is described
since its cystic transformation resembled hydatid disease through the
presence of Echinococcus. Ultrasound and computerized tomography show
ed a cystic mass within the liver of a 57 year-old woman with upper ab
dominal pain. This was interpreted as hydatid disease and an evacuatio
n procedure was performed. The histopathology of a minute specimen was
interpreted as consistent with chronic inflammation in a cyst wall. F
ive years later, a recurrence of the parasite was suspected, and compl
ete excision of the mass and resection of a bile fistula was performed
. The histopathological examination revealed a large benign schwannoma
with regressive cystic changes, proven by positive immunoreaction fbr
the neurogenic marker S-100 protein. Revision of old paraffin blocks
of tissue taken during the first operation was able to retrospectively
confirm the identical tumor by the same markers. Occurrence of schwan
nomas in parenchymatous organs or the retroperitoneum is extremely rar
e and may lead to asymptomatic growth with cystic changes, causing con
siderable difficulties in imaging procedures. Overall, the primary com
plete excision of cystic masses within the liver seems to be the best
approach in discovering their real nature and to ultimately cure them.