BACKGROUND/AIMS: Carcinoma of the gastric remnant has increased in rec
ent years, but a therapeutic strategy for this disease has not been es
tablished. This retrospective study was performed to determine the mos
t appropriate surgical procedure for carcinoma of the gastric remnant.
METHODOLOGY: A total of 25 patients who underwent operation for advan
ced carcinoma of the gastric remnant that had developed after distal g
astrectomy (13 for benign gastric diseases, B group; 12 for gastric ca
rcinoma, M group) were studied. Clinicopathological features, as well
as the status of lymph node metastasis, were investigated in the B and
M groups. RESULTS: There were more patients with carcinoma invading o
ther organs, stage IV disease, and with N2 or more lymph node metastas
is (especially, with a high metastatic rate to lymph nodes along the s
plenic artery) in the M group than in the B group. Forty percent of pa
tients in the M group were treated by left upper abdominal evisceratio
n (LUAE), but only 8% in the B group. The Survival rate (5-year, 46.0%
) of the B group was significantly higher than that (5-year, 11.9%) of
the M group. When we compared the survival rate of carcinoma of the g
astric remnant with that of primary carcinoma of the upper third of th
e stomach, there was no difference between the two groups in the curat
ive resection cases. CONCLUSIONS: Almost the same surgical strategy ca
n be adopted for the B group as for primary gastric carcinoma. On the
other hand, for the M group, a radical surgical procedure, LUAE, shoul
d be recommended.