FREQUENCY OF HLA-B27 SUBTYPES IN A DANISH POPULATION AND IN DANISH PATIENTS WITH ANKYLOSING-SPONDYLITIS

Authors
BAECH J SCHMIDTOLSEN S STEFFENSEN R VARMING K GRUNNET N JERSILD C
Citation
J. Baech et al., FREQUENCY OF HLA-B27 SUBTYPES IN A DANISH POPULATION AND IN DANISH PATIENTS WITH ANKYLOSING-SPONDYLITIS, Tissue antigens, 49(5), 1997, pp. 499-502
Citations number
18
Categorie Soggetti
Immunology,"Cell Biology
Journal title
Tissue antigens → ACNP
ISSN journal
00012815
Volume
49
Issue
5
Year of publication
1997
Pages
499 - 502
Database
ISI
SICI code
0001-2815(1997)49:5<499:FOHSIA>2.0.ZU;2-D
Abstract
Polymerase chain reaction in combination with sequence-specific oligon ucleotide probes were used to analyze nine HLA-B27 subtypes among 51 h ealthy HLA-B27 positive Danish blood donors and 30 Danish HLA-B27 posi tive patients with ankylosing spondylitis (AS). In the group of health y Danes we found two subtypes, B2705 (90.2%) and B*2702 (9.8%), howev er, among the AS patients only the B2705 subtype was detected. We did not find a significant evidence for associations between AS and a par ticular HLA-B27 subtype in a Danish population.