Purpose. To investigate the perceptions of scientists and institutiona
l representatives (IRs) to the National Institutes of Health's Office
of Research Integrity concerning appropriate punishment for unethical
research behavior. Method. In 1994-95, 606 scientists and 91 IRs rated
the ethical behaviors of and suggested appropriate punishments for pr
otagonists in randomly generated scenarios describing scientific resea
rch behaviors. The authors evaluated the relationships of the suggeste
d punishments to the protagonists' behaviors and characteristics, and
compared recommendations of the scientists and IRs. Results. The respo
ndents suggested punishments for 80% of the scenarios that were rated
unethical. Punishments were more often prescribed for behaviors rated
more unethical and for repeat offenders. The type of punishment was re
lated to the protagonist's academic status and the nature olf the unet
hical behavior. IRs proposed more and different punishments than did s
cientists. Conclusion. Scientists and IRs proposed that most unethical
research behaviors be punished. The decision to punish depended on th
e unethical level of the behavior. The type of punishment depended on
the aims: correcting the wrong, rehabilitation, or sanction. Variation
in the respondents' selections of punishments and the IRs' greater pr
opensity to punish suggest that scientists committing similar ethical
violations may receive different punishments. Explicit consideration o
f which punishment is merited under what circumstances should be under
taken by the scientific community.