L. Demartino et al., MORPHOLOGICAL-CHANGES INDUCED IN HEP-2 CELLS BY SALMONELLA-TYPHIMURIUM PORINS, Journal of submicroscopic cytology and pathology, 27(4), 1995, pp. 445-449
The effects of different doses of Salmonella typhimurium porins were i
nvestigated on human laryngeal epithelial (HEp-2) cells by fluorescenc
e and transmission electron microscopy. The changes observed in microf
ilament organization suggested an involvement of cytoskeleton in the c
ell response. Furthermore, morphologic phenomena characterized by ultr
astructural membrane modifications also involved the nuclear membrane.