Psoriasis is a common condition affecting 1.5-2.0% of Western populati
ons. It occurs equally commonly in men and women. Although it affects
mainly the skin, an associated arthritis occurs in approximately 3-4%
of those affected. It is rarely life-threatening, but is frequently th
e cause of significant morbidity, both physical and psychosocial. Mana
gement may involve topical treatments, phototherapy or photochemothera
py or systemic agents. The choice of treatment depends on a variety of
factors, including the extent and type of the cutaneous lesions, the
presence of an associated arthritis and whether the patient has any ot
her intercurrent disease. Patients receiving treatment with systemic a
gents require careful supervision, as those currently used have potent
ially serious adverse effects.