J. Utoh et al., LIFE-THREATENING REPERFUSION INJURY IN SKELETAL-MUSCLE - A SIMPLE TECHNIQUE TO CONTROL CRITICAL HYPERKALEMIA, Journal of Cardiovascular Surgery, 39(5), 1998, pp. 651-654
A 55-year-old male suffering from acute abdominal aortic occlusion due
to iatrogenic aortic dissection was urgently admitted to hospital. An
axillo-bifemoral bypass was constructed 6 hours from the onset of dis
section. Before and after revascularization, blood samples were repeat
edly obtained from a systemic artery and femoral vein. The arterial po
tassium concentration gradually increased, reaching 7.3 mM/L. Oliguria
and arrhythmias occurred, and the left lower Limb became rigid 3 hour
s after reperfusion. The femoral artery and vein were clamped and with
in 30 minutes, the arterial potassium concentration fell to 4.8 mM/L.
The urine output increased. The left lower limb was amputated, and the
patient survived. Immediately following revascularization, hyperkalem
ia may occur. Clamping of the afferent and efferent vessels is recomme
nded as a simple and practical technique to quickly control life-threa
tening hyperkalemia.