Over the past 25 years, the development of noninvasive imaging techniq
ues has allowed exquisite display of the anatomic structures of the br
ain and spinal cord in normal and disease states. CT remains useful be
cause of short imaging times, widespread availability, ease of access,
sensitive detection of calcification and hemorrhage, and resolution o
f bony detail. MRI offers superior soft-tissue contrast, excellent vis
ualization of vascular structures, fewer artifacts, and imaging in any
plane. Cost and use of ionizing radiation are considerations in choos
ing the most appropriate procedure. In the future, CT and MRI applicat
ions that concentrate on functional and physiologic display of die CNS
will add greatly to the clinical utility of these imaging tools.