Mj. Krische et al., MOLECULAR-RECOGNITION-DIRECTED SELF-ASSEMBLY OF PLEATED SHEETS FROM 2-AMINOPYRIMIDINE HYDROGEN-BONDING MOTIFS, Helvetica chimica acta, 81(11), 1998, pp. 1909-1920
The self-assembly of the ino-5,5'-(dialkylmethylidene)methylenedipyrim
idine derivatives 3a-c allows for the molecular-recognition-directed g
eneration of pleated sheets as revealed by X-rap crystallographic anal
ysis. The data provide insight into the interplay of the different str
uctural and interactional features of the molecular components in the
generation of the supramolecular assembly. The introduction of the ada
mantylidene group as in 3c leads to the dominance of the H-bonding fac
tor and the resulting formation of a regular, fully interconnected arr
ay of pleated sheet type. The results suggest further manipulation of
the interplay of the different factors to induce the self-assembly of
other supramolecular architectures.