GAS-PHASE ION-MOLECULE REACTIONS IN A MODIFIED ION-TRAP - H D EXCHANGE OF NONCOVALENT COMPLEXES AND COORDINATIVELY UNSATURATED PLATINUM COMPLEXES/

A commercially available electrospray ionization ion trap mass spectro meter has been modified to carry out gas phase ion-molecule reactions. The ability to study gas phase ion-molecule reactions in conjunction with collision induced dissociation (CID) based methods and the multis tage trapping capabilities of the ion trap have been exploited in two ways: (i) gas phase H/D exchange reactions inside the ion trap, couple d with CID tandem mass spectrometry have been used to provide insights into the reactivity of non covalent complexes of amino acids and simp le peptides, and (ii) CID prior to performing ion-molecule reactions h as been used to synthesize and examine the reactivity of coordinativel y unsaturated platinum complexes, (C) 1998 John Wiley & Sons, Ltd.