CHARACTERISTICS AND CONSEQUENCES OF FREE-FEEDING ETHANOL INGESTION DURING THE FIRST 2 POSTNATAL WEEKS OF THE RAT

Citation
Js. Lee et al., CHARACTERISTICS AND CONSEQUENCES OF FREE-FEEDING ETHANOL INGESTION DURING THE FIRST 2 POSTNATAL WEEKS OF THE RAT, Alcoholism, clinical and experimental research, 22(8), 1998, pp. 1615-1622
Citations number
38
Categorie Soggetti
Substance Abuse
ISSN journal
01456008
Volume
22
Issue
8
Year of publication
1998
Pages
1615 - 1622
Database
ISI
SICI code
0145-6008(1998)22:8<1615:CACOFE>2.0.ZU;2-W
Abstract
The present experiment used a free-feeding technique devised by Hall t o compare ingestion of ethanol end water during postnatal days 3 to 12 . More intake of ethanol than water was observed, subject to reasonabl y consistent individual differences in ethanol intake unrelated to bod y weight or general fluid intake. Relative to low ethanol consumers, p ups that ingested higher quantities of ethanol showed less ''place'' a version for stimuli associated with ethanol ingestion. High ethanol co nsumers did not, however, show an absolute conditioned place preferenc e relative to water-only controls, and they exhibited a conditioned av ersion to the odor of ethanol. These results indicate that ethanol int ake during the first two postnatal weeks is modulated by the early occ urrence of individual differences and a disposition to drink more etha nol than water, but the reinforcement effects of ethanol at this age a re unclear.