PROTEIN ADSORPTION AT A GOLD ELECTRODE STUDIED BY IN-SITU SCANNING-TUNNELING-MICROSCOPY

Authors
DAVIS JJ HALLIWELL CM HILL HAO CANTERS GW VANAMSTERDAM MC VERBEET MP
Citation
Jj. Davis et al., PROTEIN ADSORPTION AT A GOLD ELECTRODE STUDIED BY IN-SITU SCANNING-TUNNELING-MICROSCOPY, New journal of chemistry, 22(10), 1998, pp. 1119-1123
Citations number
45
Categorie Soggetti
Chemistry
Journal title
New journal of chemistry → ACNP
ISSN journal
11440546
Volume
22
Issue
10
Year of publication
1998
Pages
1119 - 1123
Database
ISI
SICI code
1144-0546(1998)22:10<1119:PAAAGE>2.0.ZU;2-3
Abstract
The in situ adsorption, under physiological conditions, of azurin mole cules at a gold electrode surface has been monitored at the molecular level by scanning tunnelling microscopy. The introduction of free cyst eine residues into the surface of the redox protein by structurally co nservative mutagenesis allows the immobilisation to be controlled in a manner in which the protein electrochemical activity is retained.