2ND RESPONSE TO IMMUNOGLOBULIN IN RECURRENT GUILLAIN-BARRE-SYNDROME

Guillain-Barre, syndrome is the most common paralytic illness among he althy adults. With modern critical care, the mortality has fallen alth ough prolonged hospitalisation and significant morbidity are common. P lasma exchange and intravenous immunoglobulin have only recently been shown to be equally efficacious; the combination of plasma exchange pl us intravenous immunoglobulin does not confer additional advantage. Co ntrary to earlier fears, immunoglobulin use is not associated with an increased relapsed rate. Some patients do benefit from a second course of immunoglobulin in recurrent Guillain-Barre syndrome.