THE MODIFICATION OF THE SPATIAL STRUCTURE OF DNA IN ITS COMPLEXES WITH CISPLATINUM

Authors
HAROUTIUNIAN SG MAMASAKHLISOV ES MOROZOV VF DALIAN EB KHACHIKIAN RE VARDEVANIAN PO KARAPETIAN AT ORIOLI P BRUNI B
Citation
Sg. Haroutiunian et al., THE MODIFICATION OF THE SPATIAL STRUCTURE OF DNA IN ITS COMPLEXES WITH CISPLATINUM, Biofizika, 42(2), 1997, pp. 372-377
Citations number
31
Categorie Soggetti
Biophysics
Journal title
Biofizika → ACNP
ISSN journal
00063029
Volume
42
Issue
2
Year of publication
1997
Pages
372 - 377
Database
ISI
SICI code
0006-3029(1997)42:2<372:TMOTSS>2.0.ZU;2-C
Abstract
The experimental and theoretical analyses of the conformational transi tions of DNA-cis-platinum complexes have been carried out. It is shown that at low concentrations of the ligand, the thermodynamic parameter s of the helix-coil transition of the complexes are not the result of the local B-->A transition.