Agm. Barrett et al., ASYMMETRIC BAYLIS-HILLMAN REACTIONS - CATALYSIS USING A CHIRAL PYRROLIZIDINE BASE, Chemical communications, (22), 1998, pp. 2533-2534
A novel chiral pyrrolizidine base 5 derived from L-proline promotes th
e Baylis-Hillman reaction of ethyl and methyl vinyl ketones with elect
ron deficient aromatic aldehydes with moderate levels of enantiomeric
excess.