DEVELOPMENT OF A SCHEME FOR GENOTYPING HELICOBACTER-PYLORI BASED ON ALLELIC VARIATION IN UREASE SUBUNIT GENES

Authors
OWEN RJ SLATER ER XERRY J PETERS TM TEARE EL GRANT A
Citation
Rj. Owen et al., DEVELOPMENT OF A SCHEME FOR GENOTYPING HELICOBACTER-PYLORI BASED ON ALLELIC VARIATION IN UREASE SUBUNIT GENES, Journal of clinical microbiology (Print), 36(12), 1998, pp. 3710-3712
Citations number
28
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology (Print) → ACNP
ISSN journal
00951137
Volume
36
Issue
12
Year of publication
1998
Pages
3710 - 3712
Database
ISI
SICI code
0095-1137(1998)36:12<3710:DOASFG>2.0.ZU;2-8
Abstract
Helicobacter pylori urease subunit genes in 383 isolates from 10 count ries were investigated by PCR restriction fragment length polymorphism (HaeIII) analysis. Eighty-two different ureAB profiles were documente d by reference to known sequences. Variation among 51% of strains was accounted for by 10 predominant patterns, which provided a unique fram ework for categorizing isolates with geographically diverse origins.