We describe the short and medium term course oi 16 patients receiving
renal retrasplants from january 1991 to august 1997 and the treatment
protocol employed according to the immunologic characteristics oi thes
e patients. The high risk patients (7 in total, sensitized or with los
s of the first graf .... than 6 months after transplant from immunolog
ic cause), were treated with corticosteroids, azathioprine, cyclospori
n A and monoclonal anti T cell antibodies (OKT3). The 9 remaining pati
ents were treated with antiliymphocyte globulin (SALT), cyclosporin A,
azathioprine and corticosteroids. The results were satisfactory; the
ac actuarial graft survival in the firs year following transplant was
85.7% for the high risk group and of 77,8% for the remainder. In concl
usion, we found that the patients at thigh risk of graft loss because
of their immunological characteristics had a similar graft survival to
that of the rest of the retransplanted patients until no increase in
complications in spite of having been treated with a potent immunosupr
esed treatment.