TREATMENT OF FELINE LEUKEMIA VIRUS-INFECTED CATS WITH PARAMUNITY INDUCER

Two placebo-controlled double-blind trials were performed to determine the therapeutic efficacy of the paramunity inducer, Baypamun(R) in fe line leukemia virus (FeLV) -infected cats under controlled conditions. In the first study, 120 cats were involved; 60 cats were treated with Baypamun(R) and 60 with a placebo preparation of virus-free cell cult ure medium. Dosage and administration of the drug over a 7-week period were performed according to the instructions given by the company. Re mission of viremia occurred in 12% and 7% of the cats treated with Bay pamun(R) and placebo, respectively. This difference was not statistica lly significant. In the second study, 30 naturally infected cats were treated in a placebo-controlled double-blind trial. In total, 20 immun ological, clinical, laboratory, and virological parameters were examin ed. No statistically significant differences could be demonstrated bet ween Baypamun(R) and placebo application. Therefore, FeLV infection wa s not influenced by Baypamun(R) treatment. (C) 1998 Elsevier Science B .V. All rights reserved.