CASTLEMANS-DISEASE AND CHROMOPHOBE CARCINOMA OF THE KIDNEY - AN INCIDENTAL ASSOCIATION

We report a ease of Castleman's disease in a 65-year-old female, revea led by a renal tumor associated with inter-aortico-cava adenopathies a nd renal chromophobe cell carcinoma. This observation points to the di fficulties in differenciating local Castleman's disease, which may be cured by surgical excision, from multicentric disease associated with a dysimmune syndrome of uncertain prognosis. The association of multic entric Castleman's disease with a carcinoma has rarely been described. It could be the emergence of a neoplasia in a context of dysimmunity or Castleman's disease might be related to the production of interleuk in 6 by a renal carcinoma.