Jm. Wieder et Rl. Moy, UNDERSTANDING BOTULINUM TOXIN - SURGICAL ANATOMY OF THE FROWN, FOREHEAD, AND PERIOCULAR REGION, Dermatologic surgery, 24(11), 1998, pp. 1172-1174
BACKGROUND. Cosmetic denervation of hyperfunctional facial lines using
botulinum toxin (Botox, Allergan,. Inc., Irvine, CA) has gained growi
ng popularity over recent years. Understanding the clinical use and ef
fects of botulinum toxin requires a thorough understanding of the musc
ular anatomy of the treatment areas. OBJECTIVE. The purpose of this ar
ticle is to review the anatomy of the frown, forehead, and periocular
regions. Function of individual muscles is discussed to understand pro
per injection technique. CONCLUSIONS. The anatomy of the frown, forehe
ad, and periocular regions is complex. Individual muscles are tightly
intertwined and treatment of one anatomic region may affect many diffe
rent muscles. A complete understanding of the anatomy of the upper fac
e is essential to ensure proper injection technique, safe and predicta
ble results as well as anticipating complications. (C) 1998 by the Ame
rican Society for Dermatologic Surgery, Inc.