TORG OSTEOLYSIS SYNDROME

We describe a 9-year-old girl who initially presented at age 4 with ev idence of arthritis in her hands, feet, and large joints. Although she had a partial response to antiinflammatory medications and had some l aboratory results consistent with inflammatory disease, radiographs sh owed carpal and tarsal osteolysis associated with interphalangeal join t erosions. There was also widening of the shafts of the metacarpals a nd metatarsals with thinning of the cortices, Based on both the clinic al progression of her illness and the radiologic characteristics, this child most likely has the Torg syndrome. (C) 1998 Wiley-Liss, Inc.