Little information is available concerning lamins in the nucleus of ge
rminal cells. In this paper we briefly describe and compare the organi
zation of A- and B-type lamins in several mammalian spermatozoa. Nucle
ar lamin B is localized primarily in the postacrosomal sheath of human
, bull and rabbit spermatozoa; lamin A/C is a major component of the e
quatorial segment in most of mammalian sperm, with the exception of ro
dents. In mouse sperm, devoid of equatorial segment, only lamin B appe
ars to be expressed. The same happens in human pathological spermatozo
a in which the equatorial segment is altered or absent.