Hn. Dogan et al., SYNTHESIS, STRUCTURE ELUCIDATION AND ANTIMICROBIAL ACTIVITY OF SOME 3-HYDROXY-2-NAPHTHOIC ACID HYDRAZIDE DERIVATIVES, Il Farmaco, 53(7), 1998, pp. 462-467
In this study, some 1,4-disubstituted thiosemicarbazide, 1,2,4-triazol
e and 1,3,4-thiadiazole type novel compounds derived from 3-hydroxy-2-
naphthoic acid hydrazide were synthesized to screen for their antimicr
obial activity. The structures of these substances were elucidated usi
ng elemental analysis and UV, H-1 NMR, and mass spectral methods. All
of these compounds were tested in vitro for their antibacterial and an
tifungal activity. (C) 1998 Elsevier Science S.A. All rights reserved.