NONPARAMETRIC IDENTIFICATION OF NONLINEAR BIOMEDICAL SYSTEMS, PART I - THEORY

The construction of mathematical models of physiological systems based on experimental data is a classic example of a nonlinear system ident ification problem. This article reviews theoretical and practical issu es relevant to nonlinear system identification in the context of biome dical engineering. Various model structures, commonly used to describe nonlinear physiological systems, are described using a common theoret ical framework and notation, to elucidate relationships among them. We then review methods for the identification of the different models us ing the common theoretical perspective, previously developed, and comp are and contrast the strengths and weaknesses of the various analysis methods in use.